PP145 VALIDATE Methodology For A Medication-Related Clinical Decision Support System: Innovating Or Going Back To Basics?

Introduction In the past decade, health technology assessment (HTA) has narrowed its scope to analysis of mainly clinical and economic benefits. However, twenty-first century challenges require need for more holistic assessments obtain accurate recommendations decision-making, as it was in HTA's foundations. VALues Doing Assessments TEchnologies (VALIDATE) methodology approaches complex technologies holistically provide a deeper understanding problem through heterogeneity stakeholders’ views, allowing comprehensive HTAs. This study aimed assess pharmaceutical decision support system (CDSS) using VALIDATE. Methods A systematic review empirical evidence on CDSS conducted according PRISMA guidelines. PubMed, Cochrane Library, Web Science databases were searched literature published between 2000 2020. Additionally, grey semi-structured interviews with different hospital stakeholders (pharmacists, physicians, computer engineers, etc.) conducted. Content used data integration. Results Preliminary results indicated consensus regarding effectiveness CDSS. Nevertheless, when including multistakeholder appeared not be fully accepted practice. The main reasons this alert fatigue disruption workflow. based information from contrasted stakeholder interview responses. Conclusions Incorporation facts values into definition scoping is essential properly conduct lack an inclusive can lead inaccurate information, particular case suboptimal implementation concerning decision-making being evaluated.